Resistance of Candida to azoles and echinocandins worldwide
نویسندگان
چکیده
منابع مشابه
Frequency of decreased susceptibility and resistance to echinocandins among fluconazole-resistant bloodstream isolates of Candida glabrata.
The echinocandin class of antifungal agents is considered to be the first-line treatment of bloodstream infections (BSI) due to Candida glabrata. Recent reports of BSI due to strains of C. glabrata resistant to both fluconazole and the echinocandins are of concern and prompted us to review the experience of two large surveillance programs, the SENTRY Antimicrobial Surveillance Program for the y...
متن کاملEmergence of Azoles Resistance Candida species in Iranian AIDS defined patients with oropharyngeal candidiasis
Background and Purpose: Oropharyngeal candidiasis (OPC) and antifungal drug resistance are major health concerns in patients with human immunodeficiency virus (HIV). The increased reports of antifungal resistance and expanding drug therapy options prompted the determination of antifungal susceptibility profile. The present study was performed to determine the antifungal susceptibility of Candid...
متن کاملAcquired resistance to echinocandins in Candida albicans: case report and review.
OBJECTIVES A patient with Candida albicans thrush and oesophagitis was treated with high doses of caspofungin but treatment eventually failed. Four C. albicans isolates were serially recovered before and after caspofungin treatment. A microbiological study was performed to characterize these four isolates. METHODS In vitro antifungal susceptibility testing was performed by the EUCAST referenc...
متن کاملpharmacotherapy of Candida Infections with echinocandins
The classic recommended antifungal agents for the treatment of invasive Candida infections were amphotericin B, a lipid formulation of amphotericin B and fluconazole in both neutropenic or nonneutropenic patients as either primary or alternative therapies. Voriconazole has been recommended when additional coverage for filamentous fungi is needed (e.g. neutropenic patients). More recently and ba...
متن کاملChloroquine sensitizes biofilms of Candida albicans to antifungal azoles.
Biofilms formed by Candida albicans, a human pathogen, are known to be resistant to different antifungal agents. Novel strategies to combat the biofilm associated Candida infections like multiple drug therapy are being explored. In this study, potential of chloroquine to be a partner drug in combination with four antifungal agents, namely fluconazole, voriconazole, amphotericin B, and caspofung...
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ژورنال
عنوان ژورنال: Clinical Microbiology and Infection
سال: 2019
ISSN: 1198-743X
DOI: 10.1016/j.cmi.2019.03.028